[In reply to GP DOCTOR ACADEMY 🧐📚]

🚨💥هنكمل سلسلة approach to Antibiotics 🚨

🦠💊 Anti-MRSA Drugs 🙆🏻

MRSA = Methicillin-resistant Staph aureus 🧱🔥

📌 Resistant to all β-lactams (except some new cephalosporins)

📌 Always consider in hospital & community infections

💊 Examples :

➡️ Vancomycin 🧱

➡️ Linezolid 💊

➡️ Daptomycin ⚡️

➡️ Ceftaroline 🩸

➡️ Different drugs, different mechanisms:

💥Vancomycin → inhibits peptidoglycan synthesis

💥Linezolid → inhibits 50S ribosome

💥Daptomycin → disrupts cell membrane

📌 All bactericidal (except Linezolid = bacteriostatic) 💥

🎯 Coverage

🟢 Gram + cocci

➡️ MRSA ✔️

➡️ MSSA ✔️

➡️ Streptococcus ✔️

🎯 لا يغطي :

❌ Gram −

❌ Anaerobes

🩺 Clinical Uses :

💉 Bacteremia / Sepsis

🫁 Pneumonia (hospital-acquired)

🦷 Skin & soft tissue infections (SSTI)

🫀 Endocarditis

🦵 Bone & joint infections

👀 إمتى أشك في MRSA 🤔

🔥 Community-acquired SSTI (abscess, cellulitis)

🏥 Hospital-acquired pneumonia / bacteremia

💉 Recent hospitalization / IV lines / dialysis

💊 Prior antibiotic use (esp. β-lactams)

🦵 Severe SSTI failing standard therapy

🧠 Notes 🔥

💣 MRSA suspect → start empiric anti-MRSA therapy

⚠️ Always check culture & sensitivity

#MRSA

#Antibiotics

#إمتياز

#GP_Doctor_Academy

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approach to Antibiotics

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